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Protein injury can be quantified via carbonyls (DNPH derivatization), nitrotyrosine as an RNS-linked marker and advanced oxidation protein products, with MS-based identification/validation wherever feasible to improve specificity and DNA damage should include 8-oxoG, abasic sites and strand breaks, interpreted cautiously because activation of repair pathways (BER/PARP) can secondarily reshape metabolic readouts (e.g., NAD⁺/ATP depletion) (Weber et al

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Third, many studies address anabolic–androgenic steroids as a broad category without distinguishing testosterone as an individual compound