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Similarly, an ASO promoting alternative splicing by the name of Milasen was designed as a personalized drug to treat an individual with Batten disease, a neurodegenerative disease characterized by blindness, an increased susceptibility to seizures, and developmental delay [102,103,104]

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In the fraction of blood cells, GPx (r = −0.354, p = 0.001) and GR activities (r = −0.225, p = 0.050) correlate negatively with ImmunolAge, whereas GSSG (r = 0.243, p = 0.02) concentration and GSSG/GSH ratio (r = 0.251, p = 0.019) correlate positively with ImmunolAge