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But a 2015 randomized control trial with 218 healthy adults found no direct links between calorie restriction and serum IGF-1 levels

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Cagrilintide is typically considered for: Adults with BMI ≥ 30 , or BMI ≥ 27 with a metabolic condition Patients who have plateaued on GLP-1 therapy Individuals with strong appetite, cravings, or binge-eating tendencies Those seeking an alternative to or enhancement of weight loss medications Who Should Avoid Cagrilintide