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This would be reminiscent of what is occurring in ALS patient spinal cord motor neurons with loss of cuproprotein function and thus overall function that precedes the eventual death of the neurons themselves (Hilton et al., 2024

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What Most Dosage Pages Get Wrong Most FOXO4-DRI dosage pages present a single figure (often 1 to 2 mg/kg) as if it were a clinical dose derived from human trials