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The upregulation of these biological pathways reflects increased activity of the immune system, regulation of intracellular structure and function, and changes in cell‒cell interactions and signal transduction in aged mouse ovarian tissues and suggest that pathways associated with inflammation and immune reactivity are relatively more active in aged mouse ovaries than in the ovaries of young mice (Figure 5D)

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Pernicious Anemia: Parenteral vitamin B12 is the recommended treatment and will be required for the remainder of the patient's life