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Its expression extends beyond plasma, permeating various tissues, including the kidney, retina, thyroid, lungs, adipose tissue, heart, liver, gastrointestinal tract, brain, mammary gland and appendix [31] (Figure 1b)

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Decreased N-Acetyl Aspartate/Myo-Inositol Ratio in the Posterior Cingulate Cortex Shown by Magnetic Resonance Spectroscopy May Be One of the Risk Markers of Preclinical Alzheimer’s Disease: A 7-Year Follow-Up Study