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5-Amino-1MQ is used by researchers as a tool to study NNMT inhibition and downstream cellular pathways in controlled laboratory models

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Considering this feature, Asn240 is able to form hydrogen bonds with the conserved water molecule, the copper-coordinating His239, the backbone carbonyl group of Glu235 and the substrate (if it contains a functional group that is able to form H-bonds at its tail)