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PURINE CATABOLISM In addition to GSH redox coupling mechanism and NO signaling, purine catabolism ( Figure 2 ) may be a previously unappreciated component of the homeostatic response of mitochondria to oxidant stress and may play a critical role in slowing progressive mitochondrial dysfunction in certain disease states (Schulz et al., 2000) and decreased DNA repair, and finally cell death

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These reactions are initiated by the antibodies immunoglobulin G (IgG) and immunoglobulin M (IgM)