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The FDA retains full discretion to accept, modify, or reject the recommendation, and formal inclusion on the 503A Bulks List requires a separate FDA rulemaking process with no announced timeline - legal analysts covering the vote have noted that a final rule could realistically take many months to over a year to materialize

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This lower activity of these enzymes occur due to the Calvin cycle malfunctioning and the occurrence of photorespiration under drought stress, which caused greater accumulation of reactive oxygen species compared with the wild type (Koffler et al