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Funding This study was supported by grants from the National Natural Science Foundation of China (30800011 and 31872621), the State Key Laboratory of Microbial Technology Foundation (M2017-01), the Natural Science Foundation of Shandong Province (ZR2020MC006), People's Republic of China, the Instrument Improvement Funds of Shandong University Public Technology Platform (ts20220104), the State Key Laboratory of Microbial Technology Open Projects Fund (Project No